Contact: Prof. L.J. Bonassar lb244@cornell.edu
Phone: 255-9381
Office: 218 Upson Hall
Tissue Engineering using CAD and
Injection Molding
The generation of new biological
tissues by the growth of cells on polymer scaffolds is known as Tissue
Engineering. This project involves the
application of engineering methods like CAD and injection molding to the hydrogel implants used for repair of defects in the
tympanic membrane. This will likely
include interactions with surgeons and researchers at
We have previously developed a
method known as tissue injection molding, in which cells are encapsulated in an
aqueous polymer solution that is subsequently crosslinked
and injected into a mold. The focus of
this project will be fabrication of implants in specified geometries,
development of techniques to quantify the mechanical performance of implants,
and the generation of SOP for implant production and testing.
An ideal background for this
project would include familiarity with standard CAD software and basic
understanding of polymer science. Tasks
for the project include mold design and fabrication, generation of shaped
implants, mechanical evaluation of implants.